Publications

Craney A*, Stastny A, Piscatelli H, Hangman A, Oommen A, Iwen PC. Evaluation of the Mabs ID/AST assay for the identification and detection of molecular resistance to amikacin and clarithromycin for the Mycobacterium abscessus complex.(submitted)

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Walsh SI, Peters DS, Smith PA, Craney A, Dix MM, Cravatt BF, Romesberg FE. Inhibition of Protein Secretion in Escherichia coli and Sub-MIC Effects of Arylomycin Antibiotics. Antimicrob Agents Chemother. 2019 Jan 29;63(2):e01253-18.

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Yeh C.H., Walsh S., Craney A., Tabor M.G., Voica A.F., Adhikary R., Morris S.E. and Romesberg F.E. Optimization of a β-Lactam Scaffold for Antibacterial Activity via the Inhibition of Bacterial Type I Signal Peptidase.  ACS Med Chem Lett. 2018. 9(4):376-380.
 

Craney A. and Romesberg F.E. Stable Signal Peptides and The Response to Secretion Stress in Staphylococcus aureus. Mbio. 2017 8(6).
 

Romesberg F.E., Craney A. Discovery of Novel Antibacterials.  Bioorg Med Chem. 2016. 15;24(24):6225-6226. doi: 10.1016/j.bmc.2016.11.046. Foreword for special issue.
 

Walsh S., Craney A. and Romesberg FE.  The contribution of type 1 bacterial signal peptidase processing to virulence.   Bioorg Med Chem. Accepted 2016. Invited Review.
 

Craney A., Dix M., Adhikary R., Cravatt B., and Romesberg F.E., An Alternative Terminal Step of the General Secretory Pathway in Staphylococcus aureus. MBio. 2015 6(4).
 

Craney A., and Romesberg F.E., The inhibition of type I bacterial signal peptidase: biological consequences and therapeutic potential. Bioorg Med Chem Lett. 2015. 25(21):4761-6. Invited review.
 

Craney A. and Romesberg F.E., A Putative Cro-Like Repressor Contributes to Arylomycin Resistance in Staphylococcus aureus. Antimicrob Agents Chemother. 2015 59(6):3066-74.
 

Jani C., Tocheva E.I., McAuley S., Craney A., Jensen G.J., Nodwell J. Streptomyces: A Screening Tool for Bacterial Cell Division Inhibitors. J Biomol Screen. 2015 20(2):275-84
 

Craney A., Ahmed S., Nodwell J., Towards a new science of secondary metabolism. J Antibiot (Tokyo). 2013 66(7):387-400. Invited review.
 

Ahmed S., Craney A., Elardo-Pimentel, S.M., Nodwell J., A synthetic, species-specific activator of secondary metabolism and sporulation in Streptomyces coelicolor. Chembiochem. 2013 14(1):83-91.
 

Craney A., Ozimok C., Elardo-Pimentel, S.M., Capretta F., Nodwell J., Chemical modification of secondary metabolism demonstrates important links between primary and secondary metabolism. Chem Biol. 2012 19(8):1020-7. 

Received Commentary: 
A magic bullet for antibiotic discovery. Chem Biol. 2012 Aug 24;19(8):932-4.
 

Craney A., Tahlan K., Andrews DW., Nodwell, J., Bacterial transmembrane proteins that lack N-terminal signal sequences. PLoS one 2011 6(5):e19421.
 

Craney A., Hohenauer T., Xu Y., Navani NK., Li Y., Nodwell, J., A synthetic luxCDABE gene cluster optimized for expression in high-GC bacteria. Nucleic Acid Res. 2007. 35(6):e46
 

Craney A*., Petrik D., Suhku A., Qiu Y., Racine-Brzostek S., Rennert H., Piscatelli H., Rathnaiah G., Hangman A., Carrie M., Cushing M. Performance Evaluation of the MatMaCorp COVID-19 2SF Assay for the Detection of SARS-CoV-2 from Nasopharyngeal Swabs. Microbiol Spectr. 2021 Sep 3;9(1):e0008321.

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​Park J, Foox J, […] Craney A, et al. System-wide transcriptome damage and tissue identity loss in COVID-19 patients. Cell Rep Med. 2022 Jan 24;3(2):100522. doi: 10.1016/j.xcrm.2022.100522. PMID: 35233546; PMCID: PMC8784611.

 

Alpert T., Brito AF, […] Craney A, et al. Early introductions and transmission of SARS-CoV-2 variant B.1.1.7 in the United States. Cell. 2021 May 13;184(10):2595-2604.e13. 

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Butler D, […] Craney A, et al. Shotgun transcriptome, spatial omics, and isothermal profiling of SARS-CoV-2 infection reveals unique host responses, viral diversification, and drug interactions. Nat Commun. 2021 Mar 12;12(1):1660. doi: 10.1038/s41467-021-21361-7.

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Velu P., Craney A., Ruggiero P., Sipley J., Cong L., Hissong E.M., Westblade L.F., Cushing M., Rennert H. Rapid implementation of SARS-CoV-2 emergency use authorization RT-PCR testing and experience at an academic medical institution. J Mol Diagn. 2021 Feb;23(2):149-158.

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Green D.A., Zucker J., Westblade L.F., Whittier S., Rennert H., Velu P., Craney A., Cushing M., Liu D., Sobieszczyk M.E., Boehme A.K., Sepulveda J.L. Clinical Performance of SARS-CoV-2 Molecular Tests. J Clin Microbiol. 2020 Jul 23;58(8):e00995-20. 

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Craney A.R., Velu P.D., Satlin M.J., Fauntleroy K.A, Callan K., Robertson A., La Spina M., Lei B., Chen A., Alston T., Rozman A., Loda M., Rennert H., Cushing M., Westblade L.F. Comparison of Two High-Throughput Reverse Transcription-PCR Systems for the Detection of Severe Acute Respiratory Syndrome Coronavirus 2. J Clin Microbiol. 2020 Jul 23;58(8):e00890-20. 

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Craney A, Miller S.  Present and Future Non-Culture Based Diagnostics: Stewardship Potentials and Considerations. Clin Lab Med (accepted, publication for May 2024)

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Liu J, Westblade LF, Wang F, Chadburn A, Fideli R, Craney A, Rand S, Cushing MM, Meng J, Zhao Z, Yang HS. Distinct Laboratory Test Result Profiles Between SARS-CoV-2 and Seasonable Influenza Infected Patients. Ann Clin Lab Sci. 2022 Nov;52(6):871-879. 

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Long SM, Chern A, Cooley V, Chung S, Feit NZ, Craney A, Simon MS, Tassler AB. Temporal Dynamics of Nasopharyngeal and Tracheal Severe Acute Respiratory Syndrome Coronavirus 2 Cycle Thresholds in Coronavirus Disease 2019 Patients With Tracheostomy. Clin Infect Dis. 2022 Oct 29;75(9):1649-1651